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Research News

ALS 'Lake Link' Tenuous
June 21, 2009
Recent media reports have raised the question of a possible link between an increased risk of developing amyotrophic lateral sclerosis (ALS) and living near Lake Mascoma in Western New Hampshire. The
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ALS 'Lake Link' Tenuous
June 18, 2009
Recent media reports have raised the question of a possible link between an increased risk of developing amyotrophic lateral sclerosis (ALS) and living near Lake Mascoma in Western New Hampshire. The
Three-Protein Repair Cluster Identified
June 18, 2009
Scientists in the United States and Japan have identified a three-protein cluster that reseals damaged muscle-fiber membranes. The findings, published June 5, 2009, in the Journal of Biological
ALS 'Lake Link' Tenuous
June 18, 2009
Recent media reports have raised the question of a possible link between an increased risk of developing amyotrophic lateral sclerosis (ALS) and living near Lake Mascoma in Western New Hampshire.
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NM Research: Successful Substitute?
June 15, 2009
A protein present in skeletal muscles during fetal development and in the heart after birth can apparently compensate for a similar protein that's missing in a small percentage of patients with the
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MD Research: Muscle-Repair Booster
June 15, 2009
In experiments in mice, Michael Rudnicki, an MDA grantee at the Sprott Center for Stem Cell Research at Ottawa Hospital Research Institute (OHRI), and colleagues, found the WNT7a protein stimulates
Stem Cell Research Brings New Hope for Muscular Dystrophy Treatment
June 11, 2009
A discovery that strengthens the body’s ability to repair muscle tissue could lead to new treatments for people with muscular dystrophy and other degenerative muscle diseases. “This discovery shows
WNT7a Protein Boosts Muscle Repair
June 11, 2009
In experiments in mice, Michael Rudnicki, an MDA grantee at the Sprott Center for Stem Cell Research at Ottawa Hospital Research Institute (OHRI), and colleagues, found the WNT7a protein stimulates
Cardiac Actin Can Substitute for Skeletal-Muscle Actin
June 11, 2009
A protein present in skeletal muscles during fetal development and in the heart after birth can apparently compensate for a similar protein that's missing in a small percentage of patients with the
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Kids’ Respiratory Needs
June 02, 2009
The proceedings of a symposium titled "Pulmonary Management of Pediatric Patients with Neuromuscular Disorders" have been published as a supplement to the May 2009 issue of the journal Pediatrics.
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Utrophin Gets In
May 27, 2009
MDA grantee James Ervasti and colleagues at the University of Minnesota-Twin Cities in Minneapolis have found that a protein known as utrophin, injected into mice lacking the dystrophin protein and
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Holes in the Walls
May 27, 2009
Proteins that keep large molecules from moving freely across blood-vessel walls in the spinal cord appear to be deficient in people with ALS (amyotrophic lateral sclerosis), MDA-supported researchers
Holes in the Walls
May 27, 2009
Proteins that keep large molecules from moving freely across blood-vessel walls in the spinal cord appear to be deficient in people with ALS (amyotrophic lateral sclerosis), MDA-supported
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Fighting the Fire
May 22, 2009
A protein called osteopontin has been implicated as a cause of some of the detrimental inflammation and scarring ("fibrosis") of muscle tissue that takes place in Duchenne muscular dystrophy (DMD).
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FA Research: Idebenone Not Effective
May 22, 2009
On May 19, 2009, Santhera Pharmaceuticals reported that a phase 3 trial of its idebenone compound Catena showed the drug was not associated with a statistically significant benefit in 70 children
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ALS Research: Survival Gene
May 21, 2009
A variant version of the gene for a protein known as KIFAP3 has been found to increase survival time in people with sporadic (nonfamilial) ALS (amyotrophic lateral sclerosis, or Lou Gehrig's disease
ALS Research: Survival Gene
May 21, 2009
A variant version of the gene for a protein known as KIFAP3 has been found to increase survival time in people with sporadic (nonfamilial) ALS (amyotrophic lateral sclerosis, or Lou Gehrig's
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DMD, MG Research: Spotlight on Prednisone
May 18, 2009
Some interesting findings about prednisone’s effect on behavior in DMD, and on drugs that may alter its usage in myasthenia gravis, were part of the 61st annual meeting of the American Academy of
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CMT Research: Gene Benefits Mice
May 18, 2009
Zarife Sahenk at Nationwide Children's Hospital and Ohio State University in Columbus, and colleagues, found mice with a disease resembling type 1A Charcot-Marie-Tooth disease (CMT) benefited from a
Searching for Signs
May 18, 2009
The 61st annual meeting of the American Academy of Neurology (AAN), held in Seattle April 25-May 2, included several ALS-related presentations. Three concerned identification of biological markers (
[title]
Searching for Signs
May 18, 2009
The 61st annual meeting of the American Academy of Neurology (AAN), held in Seattle April 25-May 2, included several ALS-related presentations. Three concerned identification of biological markers (
[title]
Stem Cells to Nerve Cells
May 11, 2009
Researchers at the Burnham Institute for Medical Research in La Jolla, Calif., and the University of California at Los Angeles, say they've developed immature nerve cells that are flexible enough to
ALS: A Vicious Cycle
May 08, 2009
A vicious cycle in which damage to nerve cells (neurons) in the spinal cord results in the loss of an important mechanism to protect neurons, causing more neuron loss, has been identified as a
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ALS: A Vicious Cycle
May 08, 2009
A vicious cycle in which damage to nerve cells (neurons) in the spinal cord results in the loss of an important mechanism to protect neurons, causing more neuron loss, has been identified as a
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Biology Prize
May 07, 2009
On May 3, 2009, molecular biologist Louis Kunkel at Children's Hospital in Boston and Harvard University, and biophysicist Kevin Campbell at the University of Iowa, received the prestigious March of

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