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Research News

Gene Modifies Severity of LGMD2C
November 18, 2009
New research has shown that a change in a gene not previously connected to type 2C limb-girdle muscular dystrophy (LGMD2C) modifies the severity of the disease in mice and is likely to do the
[title]
LGMD Research: Modifier Gene
November 17, 2009
New research has shown that a change in a gene not previously connected to type 2C limb-girdle muscular dystrophy (LGMD2C) modifies the severity of the disease in mice and is likely to do the same
Smoking Raises Risk of ALS
November 17, 2009
A new analysis says that smoking, already suspected of being a risk factor for amyotrophic lateral sclerosis (ALS), definitely is one. (See the 2004 story, Smoking Is Likely ALS Risk Factor.)
[title]
Smoking Raises Risk of ALS
November 17, 2009
A new analysis says that smoking, already suspected of being a risk factor for amyotrophic lateral sclerosis (ALS), definitely is one. (See the 2004 story, Smoking Is Likely ALS Risk Factor.) Carmel
[title]
Follistatin Genes Strengthen Muscles in Monkeys
November 12, 2009
Four macaque monkeys that received injections of genes for a protein called follistatin into upper leg muscles experienced pronounced and durable increases in muscle size and strength with no adverse
Follistatin Genes Strengthen Muscles in Monkeys
November 12, 2009
Four macaque monkeys that received injections of genes for a protein called follistatin into upper leg muscles experienced pronounced and durable increases in muscle size and strength with no adverse
MDA Grantees Prove Gene Therapy Grows Muscle Strength & Size in Primates
November 11, 2009
Four macaque monkeys that received injections of genes for a protein called follistatin into upper leg muscles experienced pronounced and durable increases in muscle size and strength and no adverse
Italian Lithium Trial Stopped Early
November 09, 2009
An Italian trial to test the effects of lithium carbonate in amyotrophic lateral sclerosis (ALS) has ended before its originally scheduled completion date because of an unusually high number of
[title]
LGMD Research: Gene Decreases Severity
November 09, 2009
New research has shown that a change in a gene not previously connected to type 2C limb-girdle muscular dystrophy (LGMD2C) modifies the severity of the disease in mice and is likely to do the same in
[title]
MLB Honors ALS Activist
November 07, 2009
The law professor and ALS activist responsible for getting Major League Baseball fired up to defeat ALS died Nov. 1. In tribute, Game 5 of the World Series, played on Nov. 2 between the New York
[title]
Italian Trial of Lithium in ALS Stopped Early
November 06, 2009
An Italian trial to test the effects of lithium carbonate in amyotrophic lateral sclerosis (ALS) has ended before its originally scheduled completion date because of an unusually high number of
[title]
SMA Research: Bolstering Backup SMN
November 06, 2009
Scientists have identified a chemical cousin of the commonly used antibiotic tetracycline that has the potential to be refined and modified into a therapy for spinal muscular atrophy (SMA). PTK-SMA1
Italian Trial of Lithium in ALS Stopped Early
November 06, 2009
An Italian trial to test the effects of lithium carbonate in amyotrophic lateral sclerosis (ALS) has ended before its originally scheduled completion date because of an unusually high number of
Disrupted Disease Process
November 04, 2009
A compound that has the potential to be refined and modified into a treatment for type 1 myotonic dystrophy (MMD1, or DM1) has been identified by researchers at the University of Oregon in Eugene,
[title]
MMD Research: Disrupted Disease Process
November 03, 2009
  A compound that has the potential to be refined and modified into a treatment for type 1 myotonic dystrophy (MMD1, or DM1) has been identified by researchers at the University of Oregon in Eugene,
[title]
ALS Research: MDA Hosts 'Think Tank'
October 30, 2009
  An all-day "think tank" to consider priorities for amyotrophic lateral sclerosis (ALS) research based on the latest information was conducted with ten of the leading scientists and clinicians in
ALS Research: MDA Hosts 'Think Tank'
October 30, 2009
An all-day "think tank" to consider priorities for amyotrophic lateral sclerosis (ALS) research based on the latest information was conducted with ten of the leading scientists and clinicians in
[title]
ALS Research: APC & ALS
October 29, 2009
A compound known as "activated protein C" (APC) that is already in use to treat severe bloodstream infections also may have benefit in ALS, according to a recently published report. APC reduced
ALS Research: APC & ALS
October 29, 2009
A compound known as "activated protein C" (APC) that is already in use to treat severe bloodstream infections also may have benefit in ALS, according to a recently published report. APC reduced
MDA Hosts One-Day ALS 'Think Tank'
October 28, 2009
Neurologist Valerie Cwik, senior executive vice president-research and medical director at MDA, and neurologist Stan Appel, a longtime MDA research grantee and director of the MDA/ALS Center at
[title]
DMD Research: US Exon Skipping Trial
October 28, 2009
The first human trial in the United States of a treatment strategy known as "exon skipping" for Duchenne muscular dystrophy (DMD) is scheduled to begin in March 2010 at Nationwide Children's Hospital
First Human Exon Skipping Trial in US Planned for 2010
October 27, 2009
Update (Jan. 23, 2013): As of early 2013, MDA's DMD Clinical Research Network includes these five sites: University of California, Davis (UC Davis); Nemours Children's Hospital in Orlando, Fla.;
Drug Used to Treat Sepsis Shows Promise in Mice with ALS
October 27, 2009
A compound known as "activated protein C" (APC) that is already in use to treat severe bloodstream infections also may have benefit in ALS, according to a recently published report. APC reduced
[title]
DMD Research: 'Remarkable' Results
October 23, 2009
Mice with a severe disease closely resembling human Duchenne muscular dystrophy (DMD) have responded extremely well to a new "exon skipping" compound that targets the specific dystrophin gene error
A Promising New Development for Treatment of Duchenne Muscular Dystrophy
October 22, 2009
A technique called exon skipping shows great potential to increase muscle strength and prolong life in people with a severe form of Duchenne muscular dystrophy (DMD). According to a study that

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