French neurologist Jean Martin Charcot establishes amyotrophic lateral sclerosis as a distinct disease
|Lou Gehrig made all Americans aware of the devastating effects of ALS.|
|MDA research grantee W. King Engel at the University of Southern California in Los Angeles tested thyrotropin-releasing hormone in ALS.|
|MDA-supported researcher and clinician Stanley H. Appel was among the first to suspect a major role for the immune system in ALS.|
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