Quest Magazine

MLB Honors ALS Activist

The law professor and ALS activist responsible for getting Major League Baseball fired up to defeat ALS died Nov. 1. In tribute, Game 5 of the World Series, played on Nov. 2 between the New York Yankees and Philadelphia Phillies, was dedicated to Michael Goldsmith, 58, a devoted baseball fan who pushed the game he loved to fight the disease he hated.

Italian Trial of Lithium in ALS Stopped Early

An Italian trial to test the effects of lithium carbonate in amyotrophic lateral sclerosis (ALS) has ended before its originally scheduled completion date because of an unusually high number of dropouts, lack of demonstrated benefit, and concerns about the drug's possible toxicity.

Italian Trial of Lithium in ALS Stopped Early

An Italian trial to test the effects of lithium carbonate in amyotrophic lateral sclerosis (ALS) has ended before its originally scheduled completion date because of an unusually high number of dropouts, lack of demonstrated benefit, and concerns about the drug's possible toxicity.

SMA Research: Bolstering Backup SMN

Scientists have identified a chemical cousin of the commonly used antibiotic tetracycline that has the potential to be refined and modified into a therapy for spinal muscular atrophy (SMA).

PTK-SMA1 works by correcting an error in a cellular process called RNA splicing, and leads to increased production of a critical protein that is deficient in this disease.

Disrupted Disease Process

A compound that has the potential to be refined and modified into a treatment for type 1 myotonic dystrophy (MMD1, or DM1) has been identified by researchers at the University of Oregon in Eugene, and the University of Rochester (N.Y.) School of Medicine and Dentistry.

MMD Research: Disrupted Disease Process

 

A compound that has the potential to be refined and modified into a treatment for type 1 myotonic dystrophy (MMD1, or DM1) has been identified by researchers at the University of Oregon in Eugene, and the University of Rochester (N.Y.) School of Medicine and Dentistry.

New Mattie Book

 MDA National Vice President Jeni Stepanek will be a guest on the November 2 broadcast of ABC's "Good Morning America" to promote the release of Messenger: The Legacy of Mattie J. T. Stepanek and Heartsongs, an inside look at the life of her famous son, who served as MDA’s National Goodwill Ambassador from 2002-2004.

ALS Research: MDA Hosts 'Think Tank'

 

An all-day "think tank" to consider priorities for amyotrophic lateral sclerosis (ALS) research based on the latest information was conducted with ten of the leading scientists and clinicians in the field and senior MDA staff in Tucson, Ariz., on Saturday, Oct. 24, 2009.

Each specialist introduced his or her area of expertise and led an approximately 20-minute discussion, gathering input and answering questions from the other participants.

Vote Abbey for Gap Kid!

Abbey Umali needs your vote.

The vivacious 10-year-old, who is MDA’s National Goodwill Ambassador, is competing for the chance to add another title to her resume: Gap Kid.

Popular international retailer Gap has launched a nationwide search for the next faces for GapKids, its kids’ clothing line. Abbey, who has a form of Charcot-Marie-Tooth disease, is in the running and could use your help to win "fan favorite."

ALS Research: APC & ALS

A compound known as "activated protein C" (APC) that is already in use to treat severe bloodstream infections also may have benefit in ALS, according to a recently published report.

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