Limb-Girdle Muscular Dystrophy (LGMD)

Jerry Mendell's Research Team Receives Award

A team headed by neurologist Jerry Mendell, a longtime MDA research grantee and director of the MDA Clinic at Nationwide Children's Hospital in Columbus, Ohio, has received the prestigious Annals of Neurology prize for an outstanding contribution to clinical neuroscience.

Induced Stem Cells Require Cautious Approach

Stem cells have been much in the news lately, including for neuromuscular diseases.

MDA Awards $13.7 Million in Research Grants

The Muscular Dystrophy Association has awarded 40 research grants totaling $13.7 million to advance the understanding of disease processes and uncover new strategies for treatments and cures of muscular dystrophy and the more than 40 other diseases in the Association's program.

The new grants were recommended by MDA's Scientific and Medical Advisory Committees and approved by MDA's Board of Directors at its July 2011 meeting.

Dwain Smith

Location

padycah, KY
2011
Full name: 
Dwain Smith
Artist: 
Dwain Smith
Disease: 
Limb-Girdle Muscular Dystrophy (LGMD)
Medium: 
Acrylic

Zeeland

Artist: 

Dwain has been painting for many years, and worked as a goldsmith and silversmith for 20 years.  He was fortunate to visit Zeeland, located in southwest Netherlands, as winter was morphing into spring.   Dwain used a heavy impasto underpainting denoting the spring winds and the earth erupting with a full bounty of blooming bulbs.  He is a member of the Paducah Area Painters Alliance and exhibits works in their co-op gallery in Paducah.

Shawl

Artist: 

Ariane was an accomplished New York artist whose works are in many permanent collections including the Metropolitan Museum of Art, New York and the Philadelphia Museum of Art.  Her stylized representational figures and exuberant use of color were distinctly her own.

Living With

Dear Friends:

When I was 4 years old, my parents took me to a specialist to find out why I walked with an unusual waddle. They learned I had limb-girdle muscular dystrophy.

Mandy Van Benthuysen

Read more ...

Clinical Trials

About clinical trials

A clinical trial is a test in humans of an experimental medication or therapy. Clinical trials are experiments, not treatments, and participation requires careful consideration.

Although it's possible to benefit from participating in a clinical trial, it's also possible that no benefit — or even harm — may occur. Keep your MDA clinic doctor informed about any clinical trial participation. (Note that MDA has no ability to influence who is chosen to participate in a clinical trial.)

Research

Throughout the 1990s and the first decade of the 21st century, MDA-supported researchers identified dozens of genes that, when defective, cause LGMD.

This gene identification work continues to the present day, along with research to determine the precise function of these genes so that missing functions can be compensated for and toxic functions can be inhibited.

Medical Management

Assistive devices

Simple devices like a cane or a long-handled reacher can make things easier as weakness progresses.

A power wheelchair or scooter becomes convenient when weakness in the pelvic girdle and upper legs causes frequent falls. People whose LGMD has reached this stage often find that a great deal of their independence returns, and they’re much less fatigued when they begin using this type of mobility equipment.

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