New research suggests that a potential strategy for treating Duchenne muscular dystrophy (DMD) may be to increase levels of heat shock proteins inside muscle fibers.
Heat shock proteins exist naturally inside cells, where they assist in the folding and unfolding of other proteins. Their levels are increased when cells are exposed to various stresses, such as high temperatures.
The Muscular Dystrophy Association has awarded $120,000 to Cambridge, Mass.-based Catabasis Pharmaceuticals as part of a strategic partnership under which the pharmaceuticals company will test two compounds called CAT-1004 and CAT-1040 in the mdx research mouse model of Duchenne muscular dystrophy (DMD).
Christian created this artwork at age 10 at an MDA-sponsored children's art workshop held June 6, 1992 in Houston. He always enjoyed swimming and fishing and going to MDA summer camp. Christian was interested in oceanliners and maritime history and went on 10 cruises.
Respondents to MDA’s Transitions Survey — in other words, people with a neuromuscular disease who are in their teens through late 30s — made it clear they had questions about the genetics of their disease, as well as questions about family planning and the value of diagnostic testing.
Bryson is a sixth-grade honor roll student, who is an extremely friendly and outgoing young man with a refreshingly positive attitude. His favorite subjects are: reading, spelling and social studies. He’s a “social butterfly’’ and often greets his friends with high-fives. .